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主营:神经科学和细胞生物学相关抗体
℡ 4000-520-616
℡ 4000-520-616
SYSY/NP-EGTA - 510 006/1 mg/510 006
产品编号:510006
市  场 价:¥7800.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$390.00
品      牌: SYSY
公      司:Synaptic Systems
公司分类:
SYSY/NP-EGTA - 510 006/1 mg/510 006
商品介绍
Cat. No.: 510 006
Amount: 1 mg
Price:390.00€
Cat.No.510006

1 mg o-nitrophenyl EGTA tetrapotassium salt dissolved in 50µl H2O (=30.5mM). HPLC analysisSpin down and store at -20°C. Protect material from light always.

Name

6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-4-(2-nitrophenyl)-tetrapotassium salt.

Molecularformula

C20H23K4N3O12. chemical structure

Molecularweight

653.81

Extinctioncoefficient

ε = 5.52 x 103 M-1 x cm-1 at260 nm in Ca2+ free 40mM HEPES / 100mM KCl buffer at pH7.2.

Photolysis quantumyield

0.23

DocumentsMSDS
Data sheet510_006.pdf

References for NP-EGTA - 510006

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.WalterAM, MüllerR, TawfikB, WierdaKD, PinheiroPS, NadlerA, McCarthyAW, ZiomkiewiczI, KruseM, ReitherG, RettigJ, et al.eLife (2017) 6: . 510006
Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.MohrmannR, deWitH, ConnellE, PinheiroPS, LeeseC, BrunsD, DavletovB, VerhageM, SørensenJBThe Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3336: 14417-30. 510006
Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release.PinheiroPS, deWitH, WalterAM, GroffenAJ, VerhageM, SørensenJBThe Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3342: 16459-70. 510006
Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system.BurgalossiA, JungS, ManKN, NairR, JockuschWJ, WojcikSM, BroseN, RheeJSNature protocols (2012) 77: 1351-65. 510006
Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.SchonnJS, vanWeeringJR, MohrmannR, SchlüterOM, SüdhofTC, deWitH, VerhageM, SørensenJBTraffic (Copenhagen, Denmark) (2010) 1111: 1415-28. 510006
Fast vesicle fusion in living cells requires at least three SNARE complexes.MohrmannR, deWitH, VerhageM, NeherE, SørensenJBScience (New York, N.Y.) (2010) 3306003: 502-5. 510006
SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.BurgalossiA, JungS, MeyerG, JockuschWJ, JahnO, TaschenbergerH, O"ConnorVM, NishikiT, TakahashiM, BroseN, RheeJS, et al.Neuron (2010) 683: 473-87. 510006
Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.CollinsSC, HoppaMB, WalkerJN, AmistenS, AbdulkaderF, BengtssonM, FearnsideJ, RamracheyaR, ToyeAA, ZhangQ, ClarkA, et al.Diabetes (2010) 595: 1192-201. 510006
Role of the synaptobrevin C terminus in fusion pore formation.NgatchouAN, KislerK, FangQ, WalterAM, ZhaoY, BrunsD, SørensenJB, LindauMProceedings of the National Academy of Sciences of the United States of America (2010) 10743: 18463-8. 510006
品牌介绍

公司历史  

Synaptic Systems由德国科学家创立

1997年,马克斯-普朗克哥廷根研究所的著名科学家创立了Synaptic Systems。由于其针对突触蛋白的成熟,高质量抗体的需求量很大,我们开始向全球科学界提供这些研究试剂的业务。

在2002年,我们建立了自己的设备齐全的研究实验室,可以改进产品并开发新抗体。迄今为止,Synaptic Systems提供了针对突触和神经科学相关蛋白的最大抗体集合之一,以及用于细胞生物学,组织病理学和高分辨率显微镜的越来越多的抗体。这些抗体中的许多已在众多影响力大的出版物中确立了自己作为参考产品的地位。 

Synaptic Systems扩大了公司渠道

多年来,我们的抗体产品组合已被精选的试剂盒和探针(如光不稳定的钙螯合剂)以及与下游免疫染色应用兼容的独特和创新的可固定膜染料(mCLINGs所补充

突触系统介绍HistoSure

2017年,我们推出了  HistoSure  产品线。HistoSure抗体已专门开发用于福尔马林固定石蜡包埋的组织。像所有SYSY产品一样,HistoSure抗体仅可通过Synaptic Systems品牌获得。它们在我们自己的工厂中进行生产和全面测试,以确保最佳的质量和可靠性。HistoSure抗体受我们特殊的HistoSure质量指南的约束(请参阅:  HistoSure抗体的验证)。 

Synaptic Systems提供定制的抗体服务

我们的Synaptic Systems抗体开发管线也可作为  定制单克隆抗体服务提供,  以探索可满足您的需求和预算的量身定制的抗体解决方案。
与学术机构和客户的紧密合作始终是将我们高技能员工的经验与合作伙伴在特定研究领域的专业知识相结合的首要任务。


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